PEGylated Network Nanostructured by Gold Nanoparticles for Electrochemical Sensing of Aromatic Redox and Nonredox Analytes

We present the design, tailoring, and physicochemical properties of a multicomponent polyethylene glycol (PEG)-based polymer doped with spherical nanoparticles modified lipoic acid derivative cyclodextrin its application for electrochemical sensing ferrocene ibuprofen at low concentrations. Each components this hybrid material has specific that can be useful preparation sensors characterized by high selectivity detection limit. Electrochemical studies have previously shown an aromatic triazole linker in structure enhances binding analyte, ensuring preconcentration on electrode and, therefore, enabling improvement sensor On other hand, introduction evenly dispersed gold matrix increases conductivity film analytical signal. The third component─a biocompatible easily wettable cross-linker, PEG─allows uninterrupted diffusion within film. This significantly performance sensor, supports further limit, enables determination analyte after saturation cavities (high concentration analyte) based response. designed was used direct indirect analytes─ferrocene ibuprofen─with very